2017Free on Pubmed
Cohn EG, Henderson GE, Appelbaum PS, for the Working Group on Representation and Inclusion in Precision Medicine Studies. Distributive justice, diversity and inclusion in precision medicine: what will success look like? Genetics in Medicine 2017;19(2):157-159. PMC5291806.
Precision medicine is based on a vision of effective preventive and therapeutic strategies grounded in precise understandings of the genetic and environmental determinants of ... Read more »
McSwiggan S, Elger B, Appelbaum PS. The forensic use of behavioral genetics in criminal proceedings: case of the MAOA-L genotype. International Journal of Law and Psychiatry 2017;50:17-23. PMC5250535.
The role of behavioral genetic evidence in excusing and mitigating criminal behavior is unclear. Research has suggested that a low activity genotype of the ... Read more »
Ahn W, Kim N, Lebowitz MS. (2017). Role of causal knowledge in reasoning about mental disorders. In MR Waldmann (Ed.), The Oxford Handbook of Causal Reasoning. New York, NY: Oxford University Press.
Causal reasoning is one of our most central cognitive competencies, enabling us to adapt to our world. Causal knowledge allows us to predict future ... Read more »
Johnston J. The nebulous ethics of human germline gene editing. Hastings Bioethics Forum, January 23, 2017
Should scientists pursue research that would enable prospective parents to edit the genes of their future children in ways that could be passed onto ... Read more »
Sabatello M, Appelbaum PS. Psychiatric genetics in child custody proceedings: ethical, legal, and social issues. Current Genetic Medicine Reports 2016;4(3):98-106. PMC5040211.
This paper considers the ethical, legal, and social issues raised by the prospect of increasing use of psychiatric genetic data in child custody litigation. ... Read more »
Lappé M. Epigenetics, media coverage, and parent responsibilities in the post-genomic era. Current Genetic Medicine Reports 2016;4(3):92-97. PMC5111809.
Environmental epigenetics is the study of how exposures and experiences can turn genes “on” or “off” without changing DNA sequence. By examining the influence ... Read more »
Lappé M. The maternal body as environment in autism science. Social Studies of Science 2016;46(5):675-700. NIHMSID 860624.
Research on autism and environmental risk factors has expanded substantially in recent years. My analysis draws attention to the regimes of perceptibility that shape ... Read more »
Appelbaum PS, Scurich N, Raad R. Effects of behavioral genetic evidence on perceptions of criminal responsibility and appropriate punishment. Psychology, Public Policy & Law 2015 May;21(2):134-144. PMC4521637.
Demonstrations of a link between genetic variants and criminal behavior have stimulated increasing use of genetic evidence to reduce perceptions of defendants' responsibility for ... Read more »
Scurich N, Appelbaum PS. The blunt-edged sword: genetic explanations of misbehavior neither mitigate nor aggravate punishment. Journal of Law and the Biosciences, published online Dec. 10, 2015, doi:10.1093/jlb/lsv053. NIHMS 735028.
Links between genetic variants and negatively valenced behaviors have stimulated intense commentary about the implications for responsibility and punishment. Previous research has suggested that ... Read more »
Parens E, Appelbaum PS (eds.). Special Report: The genetics of intelligence: ethics and the conduct of trustworthy research. Hastings Center Report 2015;45 Suppl 1:S1-72. Read more »