Sabatello M, Appelbaum PS. "Honey, I sequenced the kids": preventive genomics and the complexities of decision making for adolescents. The American Journal of Bioethics Vol. 15 , Iss. 7, 2015.
How much control should individuals have over their genomic data? Although this question has been extensively discussed in debates about return of genomic incidental ... Read more »
Johnston J. Is there room for not knowing "everything"? Hastings Center Report 2015;45(1): inside front cover.
This fall, a recurrent theme at the meetings and conferences I attended was the benefit of learning as much as possible about one's genome ... Read more »
Lebowitz MS, Ahn W. Effects of biological explanations for mental disorders on clinicians' empathy. Proceedings of the National Academy of Sciences. 2014;111(50):17786-17790.
Mental disorders are increasingly understood in terms of biological mechanisms. We examined how such biological explanations of patients’ symptoms would affect mental health clinicians’ ... Read more »
Gold A, Appelbaum PS: The inclination to evil and the punishment of crime: from the Bible to behavioral genetics. Isr J Psychiatry Rel Sciences 2014;51(3):162-168. PMC4307608
The evolving field of behavioral genetics is gradually elucidating the complex interplay between genes and environment. Scientific data pertaining to the behavioral genetics of ... Read more »
Klitzman RK, Appelbaum PS, Chung WK. Should life insurers have access to genetic test results? JAMA 2014;312(18):1855-1856. NIHMSID 628223.
Should life insurance companies have access to consumers’ genetic information? In deciding whether to sell life insurance policies and at what price, insurers routinely ... Read more »
Presidential Commission for the Study of Bioethical Issues. Anticipate and Communicate: Ethical Management of Incidental and Secondary Findings in the Clinical, Research, and Direct-to-Consumer Contexts. Washington, DC, PCSBI, December 2013, pp. 26-29.
The Bioethics Commission has adopted a definitional framework, based in part on the presentation of Erik Parens at the Bioethics Commission’s Meeting 14, that ... Read more »
Paul Appelbaum and Nicholas Scurich. "Impact of Behavioral Genetic Evidence on the Adjudication of Criminal Behavior". J Am Acad Psychiatry Law (2014) 42:91-100.
Recent advances in behavioral genetics suggest a modest relationship among certain gene variants, early childhood experiences, and criminal behavior. Although scientific research examining this ... Read more »
Paul S. Appelbaum. The Double Helix Takes the Witness Stand: Behavioral and Neuropsychiatric Genetics in Court. Neuron (2014) 82;5:946-949.
Data on neuropsychiatric and behavioral genetics have attracted legal interest, as attorneys explore their use in criminal and civil cases. These developments may assist ... Read more »
Klitzman R, Appelbaum PS, Chung W. JAMA. 2013 Jul 24;310(4):369-70. doi: 10.1001/jama.2013.41709.
In April 2013, the American College of Medical Genetics (ACMG) recommended that clinical laboratories conducting whole genome sequencing (WGS) and whole exome sequencing (WES) ... Read more »
Appelbaum PS, Waldman CR, Fyer A, Klitzman R, Parens E, Martinez J, Price WN 2nd, Chung WK. Genet Med. 2013 Oct 24. doi: 10.1038/gim.2013.145. [Epub ahead of print]
Researchers face the dilemma of how to obtain consent for return of incidental findings from genomic research. We surveyed and interviewed investigators and study ... Read more »