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Return of individual genetic results in a high-risk sample: enthusiasm and positive behavioral change

Sarah M. Hartz et al. Genetics in Medicine 2015 Abstract Purpose: The goal of this study was to examine participant responses to disclosure of genetic results in a ... Read more »

Brain-specific Foxp1 deletion impairs neuronal development and causes autistic-like behaviour

By C. Bacon et al. Abstract Neurodevelopmental disorders are multi-faceted and can lead to intellectual disability, autism spectrum disorder and language impairment. Mutations in the ... Read more »

Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder

By: S Bavamian et al. Molecular Psychiatry 2015 Abstract Bipolar disorder (BD) is a heritable neuropsychiatric disorder with largely unknown pathogenesis. Given their prominent role in brain ... Read more »

Transcriptome sequencing and genome-wide association analyses reveal lysosomal function and actin cytoskeleton remodeling in schizophrenia and bipolar disorder

By: Z Zhao et al. Molecular Psychiatry 2015 Abstract Schizophrenia (SCZ) and bipolar disorder (BPD) are severe mental disorders with high heritability. Clinicians have long noticed ... Read more »

Evaluating historical candidate genes for schizophrenia

By: M S Farrell, T Werge, P Sklar, M J Owen, R A Ophoff, M C O'Donovan, A Corvin, S Cichon, and P F ... Read more »

Altered mTORC1 signaling in multipotent stem cells from nearly 25% of patients with nonsyndromic autism spectrum disorders

By: A M Suzuki, K Griesi-Oliveira, C de Oliveira Freitas Machado, E Vadasz, E C Zachi, M R Passos-Bueno and A L Sertie Molecular Psychiatry 2015 Recent ... Read more »

Why Whole-Genome Testing Hurts More Than it Helps

By H. Gilbert Welch & Wylie Burke Los Angeles Times April 27, 2015 "President Obama proposes to plunk down $215 million on "precision medicine," and the National ... Read more »

Optogenetics and the Circuit Dynamics of Psychiatric Disease

By Karl Deisseroth, Amit Etkin, Robert C. Malenka JAMA May 14th, 2015 Abstract Optogenetics is a method for delivering millisecond-precision control (for activation or inhibition) to targeted cells ... Read more »

Splice of life

Nature Editorial May 6, 2015 Researchers, bioethicists and regulators must contribute to transparent discussions on the risks and ethics of editing human embryos. Click here for full ... Read more »

Genetically Modified Humans? Seven Reasons to Say “No”

Center for Genetics and Society May 2015 "Researchers at Sun Yat-sen University in Guangzhou, China published a paper on April 18, 2015, detailing the first use ... Read more »
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