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The Future of ELSI: Prediction and Intervention in Psychiatric, Neurologic & Behavioral Genetics

May 12, 2022 - 9:00 am

To view all of the talks please click here, or click on each individual title below.

A Two-Day Conference

Thursday, May 12, 2022 •  9am-1pm ET and Friday, May 13, 2022 • 12pm-4pm ET

This online public conference is free and open to researchers, scholars, and interested members of the Columbia University community, colleges and universities, journalists, and the general public.

This two-day conference, sponsored by the Columbia Center for Research on Ethical, Legal & Social Implications (ELSI) of Psychiatric, Neurologic & Behavioral Genetics, will begin with a review of the concepts and perspectives developed over the Center’s 12-year tenure. Then in two forward-looking sessions, we will focus on critical issues for the future of psychiatric, neurologic, and behavioral genetics.  The first, entitled Genetic Interventions for Neurodevelopmental Disorders, will address ELSI related to genetic approaches for treatment of rare neurodevelopmental disorders. The second, entitled Genomics and Prediction Science in Psychiatry, will address ELSI related to the use of polygenic risk scores for prediction in psychiatric disorders. A final session will provide the perspectives of emerging scholars on the future of ELSI research.


PROGRAM:

DAY 1 –  May 12

9:00-9:10 – Welcome and introduction to the conference: Ruth Ottman

9:10-9:55 – “The ELSI landscape and Columbia CEER: Background, Development, Progress •  Speaker: Paul Appelbaum

The Future of ELSI 1: Genetic Interventions for Neurodevelopmental Disorders 

9:55-10:40 – Current State and Future Prospects for Genetic Interventions in Neurodevelopmental Disorders”  •  Speaker: Wendy Chung

10:40-11:25 – Ethics of Genetic Therapies for Neurodevelopmental Disorders”  •  Speaker: Alison Bateman-House

11:25-11:40  –  Break

11:40-12:25  –  “Stakeholder Views of Genetic Therapies for Neurodevelopmental Disorders •  Speaker: Sandra Soo-Jin Lee

12:25-12:55  –  Panel Discussion: Wendy Chung, Alison Bateman-House, Sandra Soo-Jin Lee


DAY 2 –  May 13

12:00-12:10 – Welcome and Introduction to Day 2: Ruth Ottman

The Future of ELSI 2: Genomics and Prediction Science in Psychiatry

12:10-12:55 – Current State and Future Prospects for Genetic Prediction in Psychiatry”  •  Speaker: Steven E. Hyman

12:55-1:40 – Ethical Implications of the Clinical Use of Polygenic Risk Scores in Psychiatry”  •  Speakers: A.C. Palk and Jantina de Vries

1:40-1:55  –  Break

1:55-2:40  –  “Family and Survivor Perspectives on Genetic Testing for Suicide Risk •  Speaker: Brent Kious

2:40-3:10 – Panel Discussion: Steven E. Hyman, Jantina de Vries, Brent Kious

3:10-4:00  –  “Perspectives on the Future of ELSI •  Speakers: Alexis Walker, Matthew Lebowitz, Larry Au