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Center Research Publications

Researchers’ views on return of incidental genomic research results: qualitative and quantitative findings.

2013
Klitzman R, Appelbaum PS, Fyer A, Martinez J, Buquez B, Wynn J, Waldman CR, Phelan J, Parens E, Chung WK. Genet Med. 2013 Nov;15(11):888-95. doi: 10.1038/gim.2013.87. Epub 2013 Jun 27.
PURPOSE: Comprehensive genomic analysis including exome and genome sequencing is increasingly being utilized in research studies, leading to the generation of incidental genetic findings. It ... Read more »

Processes and factors involved in decisions regarding return of incidental genomic findings in research.

2013
Klitzman R, Buquez B, Appelbaum PS, Fyer A, Chung WK.Genet Med. 2013 Sep 26. doi: 10.1038/gim.2013.140. [Epub ahead of print]
Purpose: Studies have begun exploring whether researchers should return incidental findings in genomic studies, and if so, which findings should be returned; however, how researchers ... Read more »

Ethics and neuropsychiatric genetics: a review of major issues

2012
Hoge SK and Appelbaum PS; International Journal of Neuropsychopharmacology 2012;15(10):1547-1557. PMC3359421.
Advances in neuropsychiatric genetics hold great hopes for improved prevention, diagnosis and treatment. However, the power of genetic testing to identify individuals at increased ... Read more »

Incidental Findings in the Era of Whole Genome Sequencing?

2013
Parens E, Appelbaum AS, Chung W; Hastings Center Report, July-August 2013; 43(4):16–19
The rise of technologies that can inexpensively sequence entire genomes means that researchers and clinicians have access to ever vaster stores of genomic data, ... Read more »
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